Author: Xiao, Rui; Chen, Rongchang
Title: Neutrophil gelatinase-associated lipocalin as a potential novel biomarker for ventilator-associated lung injury Document date: 2017_4_7
ID: 3e72pzui_1
Snippet: Mechanical ventilation may induce and exacerbate lung injury, in contrast to its lifesaving effects. It has previously been demonstrated that biotrauma is an underlying mechanism of lung injury, important factors of which include inflammation and the innate immune response (1) . Biological markers of ventilator-associated lung injury (VALI) are important for early diagnosis and prognosis, and provide novel insights into the mechanisms of VALI. Cu.....
Document: Mechanical ventilation may induce and exacerbate lung injury, in contrast to its lifesaving effects. It has previously been demonstrated that biotrauma is an underlying mechanism of lung injury, important factors of which include inflammation and the innate immune response (1) . Biological markers of ventilator-associated lung injury (VALI) are important for early diagnosis and prognosis, and provide novel insights into the mechanisms of VALI. Currently identified biomarkers of VALI are key elements of the inflammatory and immune response pathways; however, the precise function of each mediator remains to be elucidated. To the best of our knowledge, no studies have validated the sensitivity or specificity of any biological markers that may aid early diagnosis or treatment of VALI (2, 3) . Further studies are required in order to identify novel, sensitive and specific biological markers.
Search related documents:
Co phrase search for related documents- biological marker and important factor: 1
- biological marker and mechanical ventilation: 1, 2
- early diagnosis and immune response: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25
- early diagnosis and important factor: 1, 2, 3, 4, 5, 6, 7, 8, 9
- early diagnosis and innate immune response: 1
- early diagnosis and lung injury: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12
- early diagnosis and mechanical ventilation: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25
- early diagnosis and novel insight: 1, 2
- elucidate remain and immune response: 1
- immune response and important factor: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25
- immune response and innate immune response: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25
- immune response and key element: 1, 2, 3, 4, 5
- immune response and lung injury: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25
- immune response and mechanical ventilation: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25
- immune response and novel insight: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13
- important factor and key element: 1
- important factor and lung injury: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15
- important factor and mechanical ventilation: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21
- important factor and novel insight: 1
Co phrase search for related documents, hyperlinks ordered by date