Author: Widagdo, W.; Okba, Nisreen M.A.; Stalin Raj, V.; Haagmans, Bart L.
Title: MERS-coronavirus: From discovery to intervention Document date: 2016_12_23
ID: 3uyuwzyr_6
Snippet: One third of the symptomatic patients develop severe pneumonia that ultimately leads to a fatal outcome. In general, these individuals are characterized by advanced age (N55 years old) and may have multiple underlying comorbidities, i.e. diabetes mellitus, asthma, chronic kidney failure, heart disease and immunosuppression [6, 17] . Most importantly, they are also prone to develop life-threatening complications, such as sepsis, acute respiratory .....
Document: One third of the symptomatic patients develop severe pneumonia that ultimately leads to a fatal outcome. In general, these individuals are characterized by advanced age (N55 years old) and may have multiple underlying comorbidities, i.e. diabetes mellitus, asthma, chronic kidney failure, heart disease and immunosuppression [6, 17] . Most importantly, they are also prone to develop life-threatening complications, such as sepsis, acute respiratory distress syndrome, and acute kidney failure [1, 6] . Therefore, rapid and effective treatment options are required in order to limit the number of cases with a fatal outcome.
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