Author: Fu, Yu; Lee, Inhan; Lee, Yong Sun; Bao, Xiaoyong
Title: Small Non-coding Transfer RNA-Derived RNA Fragments (tRFs): Their Biogenesis, Function and Implication in Human Diseases Document date: 2015_12_31
ID: 0b08jyjs_30
Snippet: The induction of tRFs is virus specific, as human metapneumovirus, a negative-sense single stranded RNA virus belonging to the Paramyxoviridae family [63] and frequent cause for lower respiratory tract infections in young children, immunocompromised patients and older adults [64] [65] [66] [67] , did not induce tRFs but gradually enhanced the expression percentage of miRNAs in a time-dependent fashion [6] . The involvement of tRFs in infectious d.....
Document: The induction of tRFs is virus specific, as human metapneumovirus, a negative-sense single stranded RNA virus belonging to the Paramyxoviridae family [63] and frequent cause for lower respiratory tract infections in young children, immunocompromised patients and older adults [64] [65] [66] [67] , did not induce tRFs but gradually enhanced the expression percentage of miRNAs in a time-dependent fashion [6] . The involvement of tRFs in infectious diseases suggests that tRFs may be targets for the development of new drugs to control viral replication.
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