Author: Zhou, ShengTao; Liu, Rui; Zhao, Xia; Huang, CanHua; Wei, YuQuan
Title: Viral proteomics: The emerging cutting-edge of virus research Document date: 2011_6_26
ID: 3ahamzjv_5
Snippet: Viruses evolved to adapt to harsh host environments by packaging their genetic material with positively charged capsid proteins and, under some circumstances, an additional tegument layer and extra membrane coats. While capsids consist of protein subunits encoded by viral genomes, envelopes comprise not only viral proteins, but also host cell proteins, lipids, and carbohydrates. Viruses orchestrate these molecular compositions to complete a wide .....
Document: Viruses evolved to adapt to harsh host environments by packaging their genetic material with positively charged capsid proteins and, under some circumstances, an additional tegument layer and extra membrane coats. While capsids consist of protein subunits encoded by viral genomes, envelopes comprise not only viral proteins, but also host cell proteins, lipids, and carbohydrates. Viruses orchestrate these molecular compositions to complete a wide spectrum of functions during infection, replication, and propagation, including assembly, exit, transmission, attachment, penetration, and uncoating [6] . Thus, viral protein composition analysis is useful for elucidating virus structure and for determining modification of virus protein expression during attachment and entry of the virus into host cells.
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