2017 ACVIM Forum Research Abstract Program

Five hundred and eighty-three cats (347 male, 235 female, 1 unknown sex) were recruited from 103 practices. Five hundred and seventeen (88.2%) were crossbred, with Burmese (n = 24; 4.1%) being the most common pure breed. Median age was 13.0 (10.4-15.0) years, median bodyweight 4.5 (3.8-5.3) kg, and median follow-up time 232 (42-596) days. One-year cumulative probability of remission was 13.1% (95% confidence interval [CI] 10-17%). Multivariable analysis revealed glucocorticoid therapy in the 90 days before diagnosis (hazard ratio [HR] 5.9; 95% CI 3.3-10.4; P < 0.0001), and Burmese breed compared to crossbred status (HR 3.7; 95% CI 1.6-8.1; P = 0.001) to be independent predictors of remission. Cumulative probability of survival 30 days' after diagnosis was 83% (95% CI 79-85%). Lack of medical anti-hyperglycemic therapy (odds ratio (OR) 14.7; 95% CI 7.5-29.0; P < 0.0001) and lower bodyweight (kg) at diagnosis (OR 1.3; 95% CI 1.0-1.7; P = 0.03) were independently associated with increased odds of death within 30 days of DM diagnosis.