Selected article for: "disease severity and progression disease severity"

Author: Mayla Borba; Fernando de Almeida Val; Vanderson Sousa Sampaio; Marcia Araujo Alexandre; Gisely Cardoso Melo; Marcelo Brito; Maria Mourao; Jose Diego Brito Sousa; djane Baia-da-Silva; Marcus Vinitius Farias Guerra; Ludhmila Hajjar; Rosemary Costa Pinto; Antonio Balieiro; Felipe Gomes Naveca; Mariana Xavier; Alexandre Salomao; Andre Siqueira; Alexandre Schwarzbolt; Julio Henrique Rosa Croda; Mauricio Lacerda Nogueira; Gustavo Romero; Quique Bassat; Cor Jesus Fontes; Bernardino Albuquerque; Claudio Daniel-Ribeiro; Wuelton Monteiro; Marcus Lacerda
Title: Chloroquine diphosphate in two different dosages as adjunctive therapy of hospitalized patients with severe respiratory syndrome in the context of coronavirus (SARS-CoV-2) infection: Preliminary safety results of a randomized, double-blinded, phase IIb clinical trial (CloroCovid-19 Study)
  • Document date: 2020_4_11
  • ID: ifxm3j4y_91
    Snippet: In order to better understand the role of CQ or HCQ in COVID-19, we recommend the following next steps: (1) trials evaluating its role as a prophylactic drug; (2) trials evaluating its efficacy against progression to severity when administered to patients with mild/moderate disease. Even if we fail to generate good evidence in time to control the current pandemic, the information will highly impact the way we deal with next coronavirus outbreaks .....
    Document: In order to better understand the role of CQ or HCQ in COVID-19, we recommend the following next steps: (1) trials evaluating its role as a prophylactic drug; (2) trials evaluating its efficacy against progression to severity when administered to patients with mild/moderate disease. Even if we fail to generate good evidence in time to control the current pandemic, the information will highly impact the way we deal with next coronavirus outbreaks in the future.

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