Title: 2017 ACVIM Forum Research Abstract Program Document date: 2017_6_15
ID: ri2w5iby_3
Snippet: Thirty-five dogs at 3 stages of MMVD were recruited based on statistical power analysis: B1 (n = 12), B2 (n = 12), and C (n = 11). Dogs in stage B2 had higher values for TAPSE, S', and Strain (P ≤ 0.05) compared to stage B1; and TAPSE compared to stage C (P = 0.019). TAPSE exceeded reference limits in 67% of B2 dogs compared with 9% in stage C (P = 0.009). This study indicates that compensated MMVD with remodeling is associated with hyperdynami.....
Document: Thirty-five dogs at 3 stages of MMVD were recruited based on statistical power analysis: B1 (n = 12), B2 (n = 12), and C (n = 11). Dogs in stage B2 had higher values for TAPSE, S', and Strain (P ≤ 0.05) compared to stage B1; and TAPSE compared to stage C (P = 0.019). TAPSE exceeded reference limits in 67% of B2 dogs compared with 9% in stage C (P = 0.009). This study indicates that compensated MMVD with remodeling is associated with hyperdynamic RVSF, but with cardiac decompensation, TAPSE, S' and Strain often normalize. These results demonstrate that RVSF differs across stages of MMVD. We aimed to evaluate the safety and efficacy of high-pressure balloon valvuloplasty (HPBVP) for treatment of canine pulmonic stenosis.
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