2017 ACVIM Forum Research Abstract Program

In this study, the prevalence of GHVs in Japanese domestic cats was surveyed and risk factor for GHV infection was determined. FcaGHV prevalence in Japan (1.4%) was lower than previously reported prevalence in other countries and areas (US, 16%; Europe, 16.2%). It was unable to determine the cause of this difference. However, Japanese isolates were identified to have close genetic relationship to domestic cat derived FcaGHV. This finding suggested that the virus is highly conserved in each animal species and GHV is harboring in host specific manner as well as other herpesviruses. The risk factor for GHV infection in Japanese cats was FIV infection and it was same as previously reported. But we have to clarify how FIV enhances the GHV infection and/or viremia. The clinical importance of GHVs infection in feline practice is still unknown. Further investigation will be necessary to identify the pathogenicity of GHVs in domestic cats. Zoetis has been conducting an ongoing surveillance program to evaluate the susceptibility trends of antimicrobial agents against canine and feline Escherichia coli (E. coli) pathogens isolated from Urinary Tract Infections (UTIs) since 2011. The data were analyzed annually and the first five years of susceptibility data for amoxicillin/clavulanic acid, ampicillin, cefovecin, cefpodoxime, ceftiofur, enrofloxacin, marbofloxacin, orbifloxacin, trimethoprim/sulfamethoxazole and cephalexin are presented here. A total of 3,300 E. coli strains, isolated as the etiological agent in cats and dogs presenting with naturally occurring UTIs and being seen at primary/general care practices were submitted to this surveillance program by 16 veterinary diagnostic laboratories throughout the United States (US) and Canada. The Minimal Inhibitory Concentrations (MICs) for all isolates were tested using a broth microdilution system (Thermo Fisher Scientific, Oakwood Village, OH) that conforms to the Clinical and Laboratory Standards Institute (CLSI) standards.