Author: Usui, Kimihito; Ichihashi, Norikazu; Yomo, Tetsuya
Title: A design principle for a single-stranded RNA genome that replicates with less double-strand formation Document date: 2015_9_18
ID: znhvdtg8_39
Snippet: The design rule described in this study is also useful in the development of an artificial cell-like system that is composed of an artificial ssRNA genome. In previous studies, we constructed an evolvable artificial cell-like system harboring an ssRNA genome (4,5) that encoded only a single gene. The design method developed in this study offers a way to introduce new genes into the ssRNA genome and to maintain the activities of the encoded genes......
Document: The design rule described in this study is also useful in the development of an artificial cell-like system that is composed of an artificial ssRNA genome. In previous studies, we constructed an evolvable artificial cell-like system harboring an ssRNA genome (4,5) that encoded only a single gene. The design method developed in this study offers a way to introduce new genes into the ssRNA genome and to maintain the activities of the encoded genes.
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