Author: WU, Hong-Xia; WANG, Hua-Lei; GUO, Xiao-Feng; YANG, Yu-Jiao; MA, Jin-Zhu; WANG, Tie-Cheng; GAO, Yu-Wei; ZHAO, Yong-Kun; YANG, Song-Tao; XIA, Xian-Zhu
Title: Adeno-Associated Viruses Serotype 2-Mediated RNA Interference Efficiently Inhibits Rabies Virus Replication In Vitro and In Vivo Document date: 2013_6_14
ID: sj9k4c3i_24
Snippet: Rabies is one of the oldest and most fatal viral diseases known to mankind, and clinical rabies, in which the virus invades the central nervous system, is incurable [17] . There is a need for development of an effective anti-rabies approach. RNA interference (RNAi) has emerged as a potential therapeutic strategy to suppress virus replication in vitro and in vivo without damaging the host cell. However, one of the potential limitations for applyin.....
Document: Rabies is one of the oldest and most fatal viral diseases known to mankind, and clinical rabies, in which the virus invades the central nervous system, is incurable [17] . There is a need for development of an effective anti-rabies approach. RNA interference (RNAi) has emerged as a potential therapeutic strategy to suppress virus replication in vitro and in vivo without damaging the host cell. However, one of the potential limitations for applying this technology is developing an effective and targeted delivery tool.
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