Selected article for: "important factor and international license"
Author: Zonghao Zhao; Jiajia Xie; Ming Yin; Yun Yang; Hongliang He; Tengchuan Jin; Wenting Li; Xiaowu Zhu; Jing Xu; Changcheng Zhao; Lei Li; Yi Li; Hylemariam Mihiretie Mengist; Ayesha Zahid; Ziqin Yao; Chengchao Ding; Yingjie Qi; Yong Gao; Xiaoling Ma
Title: Clinical and Laboratory Profiles of 75 Hospitalized Patients with Novel Coronavirus Disease 2019 in Hefei, China
  • Document date: 2020_3_6
    • ID: a5x5ga60_11
    Snippet: The copyright holder for this preprint . https://doi.org/10.1101/2020.03.01.20029785 doi: medRxiv preprint more than 50% patients. The most significant was the decreased CD4 + T cell counts. 194 Previous studies of patients in Wuhan suggested virus invasion could induce a 195 cytokine storm syndrome (CRS) [5, 8] . Of the 14 patients with elevated IL-6, LYM%, 196 CD4 + and CD8 + T cell counts were significantly decreased and NEU%, CRP and 197 LDH .....
    Document: The copyright holder for this preprint . https://doi.org/10.1101/2020.03.01.20029785 doi: medRxiv preprint more than 50% patients. The most significant was the decreased CD4 + T cell counts. 194 Previous studies of patients in Wuhan suggested virus invasion could induce a 195 cytokine storm syndrome (CRS) [5, 8] . Of the 14 patients with elevated IL-6, LYM%, 196 CD4 + and CD8 + T cell counts were significantly decreased and NEU%, CRP and 197 LDH levels increased significantly. Elevated IL-6 may be an important factor leading 198 to T lymphocytes damage and cellular immune deficiency. IL-6 could also be used as 199 an indicator to evaluate infection severity. Therefore, we conclude that IL-6 may be an Currently, there is no specific therapy for patients with new coronavirus pneumonia. 220 The pathologic mechanisms of disease progression and exacerbation are also unclear. 221 How to relieve the clinical symptoms of critically ill patients, and reduce the severity 222 . CC-BY-NC-ND 4.0 International license It is made available under a is the author/funder, who has granted medRxiv a license to display the preprint in perpetuity. CC-BY-NC-ND 4.0 International license It is made available under a is the author/funder, who has granted medRxiv a license to display the preprint in perpetuity. 269 We declare no competing interests.

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