Selected article for: "antiviral action and chloroquine antiviral effect"
Author: Borges, Marcos Carvalho; Castro, Luiza Antunes; da Fonseca, Benedito Antonio Lopes
Title: Chloroquine use improves dengue-related symptoms
  • Document date: 2013_8_23
    • ID: s8tq6d68_19
    Snippet: We hypothesised that the clinical benefit observed in dengue patients treated with chloroquine could be due to the drug's anti-inflammatory effects, particularly because chloroquine is a tumour necrosis factor (TNF)-α inhibitor and some of the clinical manifestations in dengue patients are due to high levels of serum TNF-α (Hober et al. 1993 , Pinto et al. 1999 , Gandini et al. 2011 . Another possible effect of chloroquine in dengue patients co.....
    Document: We hypothesised that the clinical benefit observed in dengue patients treated with chloroquine could be due to the drug's anti-inflammatory effects, particularly because chloroquine is a tumour necrosis factor (TNF)-α inhibitor and some of the clinical manifestations in dengue patients are due to high levels of serum TNF-α (Hober et al. 1993 , Pinto et al. 1999 , Gandini et al. 2011 . Another possible effect of chloroquine in dengue patients could be related to its antiviral action, lowering the viral load and thus the degree of immune system activation.

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