Selected article for: "domestic cat and granulomatous inflammation"
Author: DOKI, Tomoyoshi; TAKANO, Tomomi; HOHDATSU, Tsutomu
Title: Development of a mouse-feline chimeric antibody against feline tumor necrosis factor-alpha
  • Document date: 2016_6_4
    • ID: y0x0quha_1
    Snippet: Feline infectious peritonitis virus (FIP virus: FIPV), a feline coronavirus (FCoV) of the family Coronaviridae, causes a fatal disease called FIP in wild and domestic cat species. Several organs, including the liver, lungs, spleen and central nervous system, are affected in cats that develop FIP, and the formation of lesions in these organs is accompanied by necrosis and pyogenic granulomatous inflammation [13] . Pleural effusion and ascitic flui.....
    Document: Feline infectious peritonitis virus (FIP virus: FIPV), a feline coronavirus (FCoV) of the family Coronaviridae, causes a fatal disease called FIP in wild and domestic cat species. Several organs, including the liver, lungs, spleen and central nervous system, are affected in cats that develop FIP, and the formation of lesions in these organs is accompanied by necrosis and pyogenic granulomatous inflammation [13] . Pleural effusion and ascitic fluid were reported to accumulate in some cats. Macrophages/monocytes play an important role in the pathogenesis of FIP. For example, differences in the proliferation of macrophages/monocytes were shown to be related to differences in pathogenicity between feline enteric coronavirus (FECV) and FIPV [2, 16] . FECV and FIPV cannot be serologically or genetically distinguished from each other; however, FECV infection is normally asymptomatic in cats.

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