Title: Research Communications of the 24th ECVIM-CA Congress Document date: 2015_1_10
ID: r59usk02_237
Snippet: Conflicts of interest: ZHP and SG are supported by the EC FP7 Marie-Curie programme: NephroTools. The device development was supported by the FP7 activity: PLACE-it.NG is owner of a patent covering FITC-sinistrin and the technology for its measurement. Excretion of urinary biomarkers of renal damage should occur at an early stage of chronic kidney disease (CKD), thus facilitating earlier diagnosis of renal disease. Albumin and cystatin C in the r.....
Document: Conflicts of interest: ZHP and SG are supported by the EC FP7 Marie-Curie programme: NephroTools. The device development was supported by the FP7 activity: PLACE-it.NG is owner of a patent covering FITC-sinistrin and the technology for its measurement. Excretion of urinary biomarkers of renal damage should occur at an early stage of chronic kidney disease (CKD), thus facilitating earlier diagnosis of renal disease. Albumin and cystatin C in the renal ultrafiltrate are mostly reabsorbed by the proximal tubular cells, therefore increased urinary excretion of albumin and cystatin C (UAC and UCysC) would be expected to correlate with the presence of renal tubular damage and CKD. The aim of this study was to establish biological validity of two particle enhanced turbidimetric assays (PETIAs) for the measurement of albumin and cystatin C (previously validated for use in feline urine) by comparing the UAC and UCysC between non-azotaemic cats and cats with azotaemic CKD.
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