Author: Langenmayer, M.C.; Jung, S.; Majzoub-Altweck, M.; Trefz, F.M.; Seifert, C.; Knubben-Schweizer, G.; Fries, R.; Hermanns, W.; Gollnick, N.S.
Title: Zinc Deficiency-Like Syndrome in Fleckvieh Calves: Clinical and Pathological Findings and Differentiation from Bovine Hereditary Zinc Deficiency Document date: 2018_2_9
ID: qui29pis_32
Snippet: Combining the available information and the present cases, the role of PLD4 in calves is very likely associated with immunological functions and keratinocyte differentiation. Infection of the respiratory and digestive tract and skin suggest some kind of immunosuppression. Regarding PLD4 and PLD function in microglia 4 and neutrophils, 33 respectively, the innate immune system is likely compromised. Hyper-and parakeratosis suggest a role of PLD4 i.....
Document: Combining the available information and the present cases, the role of PLD4 in calves is very likely associated with immunological functions and keratinocyte differentiation. Infection of the respiratory and digestive tract and skin suggest some kind of immunosuppression. Regarding PLD4 and PLD function in microglia 4 and neutrophils, 33 respectively, the innate immune system is likely compromised. Hyper-and parakeratosis suggest a role of PLD4 in the keratinization process and differentiation of keratinocytes.
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