Author: Kim, Yeong Hoon; Lee, Jihoo; Kim, Young-Eun; Chong, Chom-Kyu; Pinchemel, Yanaihara; Reisdörfer, Francis; Coelho, Joyce Brito; Dias, Ronaldo Ferreira; Bae, Pan Kee; Gusmão, Zuinara Pereira Maia; Ahn, Hye-Jin; Nam, Ho-Woo
Title: Development of a Rapid Diagnostic Test Kit to Detect IgG/IgM Antibody against Zika Virus Using Monoclonal Antibodies to the Envelope and Non-structural Protein 1 of the Virus Document date: 2018_2_28
ID: skzidybm_3
Snippet: Thus, laboratory diagnosis of ZIKV infection is very important, but remains challenging, due to a limited time window of possible virus detection, whereby patients tested more than 1 to 2 weeks post-symptom onset are difficult to diagnose [26] [27] [28] . There is therefore a need for an accurate diagnostic approach that will prolong the diagnostic period [29] . In this study, we developed an RDT kit (Zika RDT) for detecting IgG/ IgM antibody aga.....
Document: Thus, laboratory diagnosis of ZIKV infection is very important, but remains challenging, due to a limited time window of possible virus detection, whereby patients tested more than 1 to 2 weeks post-symptom onset are difficult to diagnose [26] [27] [28] . There is therefore a need for an accurate diagnostic approach that will prolong the diagnostic period [29] . In this study, we developed an RDT kit (Zika RDT) for detecting IgG/ IgM antibody against ZIKV using monoclonal antibodies to the E and NS1 proteins of ZIKV.
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