Title: RESEARCH COMMUNICATIONS OF THE 28th ECVIM-CA CONGRESS Document date: 2018_12_19
ID: r79h9yzz_588
Snippet: Dogs with leptospirosis (n=211) or acute kidney injury not due to leptospirosis (AKIâ€nL, n=119) treated at the Vetsuisse Faculty Bern between 2011 and 2017 were included if they had a complete vaccination history. A diagnosis of leptospirosis was confirmed based on compatible clinical findings and the presence of at least one of the following: positive single MAT titre ≥1:800 (n=66), MAT seroconversion (n=102), positive IgM lateral flow assay.....
Document: Dogs with leptospirosis (n=211) or acute kidney injury not due to leptospirosis (AKIâ€nL, n=119) treated at the Vetsuisse Faculty Bern between 2011 and 2017 were included if they had a complete vaccination history. A diagnosis of leptospirosis was confirmed based on compatible clinical findings and the presence of at least one of the following: positive single MAT titre ≥1:800 (n=66), MAT seroconversion (n=102), positive IgM lateral flow assay (n=16), positive urine RTâ€PCR (n=4), or strong clinical suspicion not confirmed serologically due to early death (n=23). Control dogs were diagnosed with AKIâ€nL based on a convincing alternative diagnosis and at least a negative serology. Annual incidences and vaccine effectiveness were compared between groups, the latter being expressed as odds ratio (OR) for being diagnosed with leptospirosis.
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