Author: Chu, Helen Y.; Renaud, Christian; Ficken, Elle; Thomson, Blythe; Kuypers, Jane; Englund, Janet A.
Title: Respiratory Tract Infections Due to Human Metapneumovirus in Immunocompromised Children Document date: 2014_10_21
ID: ujvbm6ae_21
Snippet: Human metapneumovirus infections in our immunocompromised patient population was associated with high rates of LRTI at presentation, and an attributable mortality of 5%, rates substantially higher than that in the general population where hMPV is most commonly a self-limited URTI. In our study, 12 (23%) of immunocompromised children with hMPV were classified as having severe disease, and neutropenia was identified as a significant risk factor for.....
Document: Human metapneumovirus infections in our immunocompromised patient population was associated with high rates of LRTI at presentation, and an attributable mortality of 5%, rates substantially higher than that in the general population where hMPV is most commonly a self-limited URTI. In our study, 12 (23%) of immunocompromised children with hMPV were classified as having severe disease, and neutropenia was identified as a significant risk factor for disease severity. This rate is comparable or even higher than previous rates reported in seriously immunocompromised adult patients [13] .
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