Selected article for: "adaptive innate and low concentration"
Author: Ding, Peiyang; Zhang, Teng; Li, Yafei; Teng, Man; Sun, Yaning; Liu, Xiao; Chai, Shujun; Zhou, Enmin; Jin, Qianyue; Zhang, Gaiping
Title: Nanoparticle orientationally displayed antigen epitopes improve neutralizing antibody level in a model of porcine circovirus type 2
  • Document date: 2017_7_24
    • ID: upb97on4_44
    Snippet: We next investigated the immunostimulatory effect of the Cap-AuNP conjugates and detected four types of cytokines: IL-12 ( Figure 5C ), TNF-α ( Figure 5D ), IL-1β ( Figure 5E ), and IL-18 ( Figure 5F ). IL-12 and TNF-α play pivotal roles in eliciting innate immune responses and regulation of adaptive immune responses, mainly produced by T cells and APCs. 38, 39 Although Cap could induce low-concentration IL-12 and high-concentration TNF-α, Au.....
    Document: We next investigated the immunostimulatory effect of the Cap-AuNP conjugates and detected four types of cytokines: IL-12 ( Figure 5C ), TNF-α ( Figure 5D ), IL-1β ( Figure 5E ), and IL-18 ( Figure 5F ). IL-12 and TNF-α play pivotal roles in eliciting innate immune responses and regulation of adaptive immune responses, mainly produced by T cells and APCs. 38, 39 Although Cap could induce low-concentration IL-12 and high-concentration TNF-α, AuNPs had no influence on the

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