Author: Mohamed, Fakry F.; Ktob, Gamelat K.F.; Ismaeil, Mohamed E.A.; Ali, Ahmed A.H.; Goyal, Sagar M.
Title: Phylogeny of bovine norovirus in Egypt based on VP2 gene Document date: 2018_4_13
ID: rah5p1y4_30
Snippet: Fourteen unique aa substitution mutations were detected in both strains (Fig. 3) . Neither insertions nor deletions were observed. Such variations may play a role in classifying closely-related BNoV strains. Study strains shared identities of 81.8% and 88.5% at nt and aa, respectively. The nt and aa identities ( Table 2 ) further confirm the clustering made by the phylogenetic tree. It is expected for norovirus capsid proteins, particularly the V.....
Document: Fourteen unique aa substitution mutations were detected in both strains (Fig. 3) . Neither insertions nor deletions were observed. Such variations may play a role in classifying closely-related BNoV strains. Study strains shared identities of 81.8% and 88.5% at nt and aa, respectively. The nt and aa identities ( Table 2 ) further confirm the clustering made by the phylogenetic tree. It is expected for norovirus capsid proteins, particularly the VP2, to exhibit broad sequence variability [15] . The hypervariability of VP2 sequences was assumed to be functionally-related to those occurring in the P2 domain of VP1 protein [25] and this may affect the viral pathogenesis.
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