Author: Tristan de Jong; Victor Guryev; Yury M. Moshkin
Title: Discovery of pharmaceutically-targetable pathways and prediction of survivorship for pneumonia and sepsis patients from the view point of ensemble gene noise Document date: 2020_4_11
ID: f5w05rc2_24
Snippet: Here we attempted a dissection of molecular mechanisms of human pathology, exemplified by H1N1 infection, CAP and sepsis, through a prism of ensemble gene noise. Unlike classical DGE, ensemble gene noise allows for the identification of imbalances in the expression of entire gene circuits, rather than individual genes on the level of stoichiometry and gene noise......
Document: Here we attempted a dissection of molecular mechanisms of human pathology, exemplified by H1N1 infection, CAP and sepsis, through a prism of ensemble gene noise. Unlike classical DGE, ensemble gene noise allows for the identification of imbalances in the expression of entire gene circuits, rather than individual genes on the level of stoichiometry and gene noise.
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