Author: Gallo, Oreste; Trotta, Michele; Orlando, Pietro; Maggiore, Giandomenico; Bicci, Eleonora; Giovanni Locatello, Luca
Title: “SARS-CoV-2 in upper and lower airway samples of a laryngectomized patient: new insights and many lessons†Cord-id: 6hqr4ei9 Document date: 2020_6_4
ID: 6hqr4ei9
Snippet: • Despite upper airways are functionally excluded, we are the first to report the presence of SARS-CoV-2 in the nasopharyngeal swab of a laryngectomized patient; • The primary nasal viral infection is not a mere anatomical constraint but it underlies an immunological priming that can condition the systemic inflammatory response; • Head and neck cancer patients have very often a significant history of smoking exposure and this makes them more susceptible to SARS-CoV-2 as well as to the deve
Document: • Despite upper airways are functionally excluded, we are the first to report the presence of SARS-CoV-2 in the nasopharyngeal swab of a laryngectomized patient; • The primary nasal viral infection is not a mere anatomical constraint but it underlies an immunological priming that can condition the systemic inflammatory response; • Head and neck cancer patients have very often a significant history of smoking exposure and this makes them more susceptible to SARS-CoV-2 as well as to the development of multiple malignancies.
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