Selected article for: "real time pcr and sequencing analysis"
Author: Jie Liu; Liu Ouyang; Pi Guo; Hai sheng Wu; Peng Fu; Yu liang Chen; Dan Yang; Xiao yu Han; Yu kun Cao; Osamah Alwalid; Juan Tao; Shu yi Peng; He shui Shi; Fan Yang; Chuan sheng Zheng
Title: Epidemiological, Clinical Characteristics and Outcome of Medical Staff Infected with COVID-19 in Wuhan, China: A Retrospective Case Series Analysis
  • Document date: 2020_3_13
    • ID: hnm54k4r_1
    Snippet: In December, 2019, a group of novel atypical pneumonia patients with uncertain etiology but mostly linked to the Huanan Seafood Wholesale Market emerged in Wuhan, China [1] . A later confirmed pathogen of this previously unknown pneumonia was described as a novel coronavirus, currently named as severe acute respiratory syndrome coronavirus 2 (SARS-Cov-2; previously known as 2019nCoV), was ascertained by unbiased sequencing analysis of lower respi.....
    Document: In December, 2019, a group of novel atypical pneumonia patients with uncertain etiology but mostly linked to the Huanan Seafood Wholesale Market emerged in Wuhan, China [1] . A later confirmed pathogen of this previously unknown pneumonia was described as a novel coronavirus, currently named as severe acute respiratory syndrome coronavirus 2 (SARS-Cov-2; previously known as 2019nCoV), was ascertained by unbiased sequencing analysis of lower respiratory tract samples from early cases on 7 Jan 2020, following which the protocol of real-time reverse-transcriptase polymerase chain reaction (RT-PCR) assay for this novel coronavirus had also been developed [2] [3] [4] [5] [6] [7] . In fact, the epidemics of the two other novel coronaviruses, namely severe acute respiratory syndrome coronavirus (SARS-CoV) and Middle East respiratory syndrome coronavirus (MERS-CoV), have posed a huge threat to public health in the past two decades [8, 9] . SARS-Cov-2 in this outbreak, like the previous two viruses, is also categorized within the same genus of the subfamily Orthocoronavirinae within the family Coronaviridae, but shows a strong affinity for human respiratory receptors [10, 11] .

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