Author: Chi Heem Wong; Kien Wei Siah; Andrew W Lo
Title: Estimating Probabilities of Success of Clinical Trials for Vaccines and Other Anti-Infective Therapeutics Document date: 2020_4_14
ID: fnrm6a79_34
Snippet: We find that companies have been most successful in developing non-vaccine treatments for diseases transmitted between humans through the air, with 50.0% (SE: 25.0%) of all drug development programs making it from phase 1 to regulatory approval (see Figure 6b ). Unfortunately, this is based on only four drug development programs and may not be indicative of the general trend. Treatments for diseases that transmit through 'human to human (others)'.....
Document: We find that companies have been most successful in developing non-vaccine treatments for diseases transmitted between humans through the air, with 50.0% (SE: 25.0%) of all drug development programs making it from phase 1 to regulatory approval (see Figure 6b ). Unfortunately, this is based on only four drug development programs and may not be indicative of the general trend. Treatments for diseases that transmit through 'human to human (others)' have an overall PoS of 21.5% (SE: 1.2%) while no approval is observed for diseases transmitted through 'animal bites' or 'contaminated food or water'. . CC-BY 4.0 International license It is made available under a author/funder, who has granted medRxiv a license to display the preprint in perpetuity.
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