Selected article for: "International license and risk factor"
Author: Shitao Rao; Alexandria Lau; Hon-Cheong So
Title: Exploring diseases/traits and blood proteins causally related to expression of ACE2, the putative receptor of 2019-nCov: A Mendelian Randomization analysis
  • Document date: 2020_3_8
    • ID: myh73pe6_6
    Snippet: The concept of MR is akin to randomized controlled trials (RCT). For example, consider a study on the causal effect of lipid on the risk of a certain disease. Subjects who have inherited lipid-lowering alleles at a locus (or a set of such alleles at multiple loci) will have lower lipid levels on average, which is analogous to receiving lipid-lowering drugs in an RCT 20 . The random allocation of alleles at conception is similar to random assignme.....
    Document: The concept of MR is akin to randomized controlled trials (RCT). For example, consider a study on the causal effect of lipid on the risk of a certain disease. Subjects who have inherited lipid-lowering alleles at a locus (or a set of such alleles at multiple loci) will have lower lipid levels on average, which is analogous to receiving lipid-lowering drugs in an RCT 20 . The random allocation of alleles at conception is similar to random assignment of treatment in an RCT. As a result, the chance of spurious associations due to known or unknown confounders is reduced due to the 'random assignment' of treatment or risk factor. Another important point to . CC-BY-NC-ND 4.0 International license It is made available under a author/funder, who has granted medRxiv a license to display the preprint in perpetuity.

    Search related documents:
    Co phrase search for related documents
    • causal effect and certain disease risk: 1
    • causal effect and control trial: 1
    • causal effect and lipid causal effect: 1, 2
    • cc NC ND International license and certain disease: 1
    • cc NC ND International license and International license: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25
    • certain disease and International license: 1, 2, 3, 4
    • important point and International license: 1, 2