Author: Standing, Joseph F.
Title: Response to: Optimizing Hydroxychloroquine Dosing for Patients With COVIDâ€19: An Integrative Modeling Approach for Effective Drug Repurposing: Quantitative Clinical Pharmacology Input to SARSâ€CoVâ€2 Therapeutics Should Be Based on Robust Data Cord-id: i0gw63l3 Document date: 2020_5_20
ID: i0gw63l3
Snippet: With impressive speed Garcia-Cremades et al[1] have modelled the association between hydroxychloroquine (HCQ) and viral load, merging literature in vitro data and data from a recently published clinical study (which as of April 11 2020 is under investigation by the publisher[2]). Whilst the authors are to be commended on bringing quantitative clinical pharmacology insight to this health emergency, caution is required on interpreting their results.
Document: With impressive speed Garcia-Cremades et al[1] have modelled the association between hydroxychloroquine (HCQ) and viral load, merging literature in vitro data and data from a recently published clinical study (which as of April 11 2020 is under investigation by the publisher[2]). Whilst the authors are to be commended on bringing quantitative clinical pharmacology insight to this health emergency, caution is required on interpreting their results.
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