Author: Shannon C. Brady; Stefan Zdraljevic; Karol W. Bisaga; Robyn E. Tanny; Daniel E. Cook; Daehan Lee; Ye Wang; Erik C. Andersen
Title: A nematode-specific gene underlies bleomycin-response variation in Caenorhabditis elegans Document date: 2019_3_1
ID: 75v2qt1w_14
Snippet: By contrast, the jmjd-5 deletion alleles in the N2 and the CB4856 backgrounds were each more 530 resistant to bleomycin than their respective parental strains ( Figure 3B, File S7 , ECA1047 vs. 531 CB4856 p = 3.8e-10, ECA1048 vs. CB4856 p = 0.026, ECA1051 vs. N2 p = 7.4e-4, ECA1052 532 vs. N2 p = 2.9e-6, Tukey HSD). However, we also noted that these strains were more sensitive in 533 the control condition than other deletion strains ( Figure S8, .....
Document: By contrast, the jmjd-5 deletion alleles in the N2 and the CB4856 backgrounds were each more 530 resistant to bleomycin than their respective parental strains ( Figure 3B, File S7 , ECA1047 vs. 531 CB4856 p = 3.8e-10, ECA1048 vs. CB4856 p = 0.026, ECA1051 vs. N2 p = 7.4e-4, ECA1052 532 vs. N2 p = 2.9e-6, Tukey HSD). However, we also noted that these strains were more sensitive in 533 the control condition than other deletion strains ( Figure S8, File S1, File S7) . Therefore, the 534 relative increased bleomycin resistance observed in the jmjd-5 deletion strains could be caused 535 by their increased sensitivity in the control condition. 536
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