Author: Amir Saberi; Anastasia A. Gulyaeva; John L. Brubacher; Phillip A. Newmark; Alexander E. Gorbalenya
Title: A planarian nidovirus expands the limits of RNA genome size Document date: 2018_4_11
ID: gwgflckq_17
Snippet: Nidoviruses use -1 programmed ribosomal frameshifting (PRF) at the ORF1a/1b border to attenuate the synthesis of major replicative enzymes upon genome translation (46) . We located a potential -1 PRF signal in the canonical position in the PSCNV genome (SI Text). This signal could potentially attenuate in-frame translation downstream of the ORF1a-like region (Fig. 4A ) similar to a mechanism used by encephalomyocarditis virus (47) ......
Document: Nidoviruses use -1 programmed ribosomal frameshifting (PRF) at the ORF1a/1b border to attenuate the synthesis of major replicative enzymes upon genome translation (46) . We located a potential -1 PRF signal in the canonical position in the PSCNV genome (SI Text). This signal could potentially attenuate in-frame translation downstream of the ORF1a-like region (Fig. 4A ) similar to a mechanism used by encephalomyocarditis virus (47) .
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