Author: Dijkman, Ronald; Mulder, H. Lie; Rumping, Lynne; Kraaijvanger, Ilse; Deijs, Martin; Jebbink, Maarten F.; Verschoor, Ernst J.; van der Hoek, Lia
Title: Seroconversion to HCoV-NL63 in Rhesus Macaques Cord-id: uf9sx5qi Document date: 2009_10_30
ID: uf9sx5qi
Snippet: HCoV-NL63 is a recently identified respiratory virus. Its pathogenesis has not been fully unraveled because an animal model is currently lacking. Here we examined whether rhesus macaques encounter HCoV-NL63 infections during life, by examining the levels of antibodies to HCoV-NL63 in time. The animals were followed for 7 up till 19 years, and in three animals we observed a steep rise in antibodies during follow up, indicative of a natural infection with HCoV-NL63.
Document: HCoV-NL63 is a recently identified respiratory virus. Its pathogenesis has not been fully unraveled because an animal model is currently lacking. Here we examined whether rhesus macaques encounter HCoV-NL63 infections during life, by examining the levels of antibodies to HCoV-NL63 in time. The animals were followed for 7 up till 19 years, and in three animals we observed a steep rise in antibodies during follow up, indicative of a natural infection with HCoV-NL63.
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