Selected article for: "odd ratio and pulmonary disease"

Author: Gómez, Carlos Andrés; Sun, Cheuk-Kwan; Tsai, I-Ting; Chang, Yang-Pei; Lin, Ming-Chung; Hung, I-Yin; Chang, Ying-Jen; Wang, Li-Kai; Lin, Yao-Tsung; Hung, Kuo-Chuan
Title: Mortality and risk factors associated with pulmonary embolism in coronavirus disease 2019 patients: a systematic review and meta-analysis
  • Cord-id: cofdpw26
  • Document date: 2021_8_6
  • ID: cofdpw26
    Snippet: To determine, in patients with coronavirus disease 2019 (COVID-19) infection, the associations of pulmonary embolism (PE) with mortality and risk factors for PE as well as the therapeutic benefit of anticoagulant prophylaxis. Embase, PubMed, Cochrane controlled trials register, and Web of Science databases were searched from inception to October 10, 2020. We included all published trials on PE in patients diagnosed with COVID-19 with eligibility of the trials assessed following the PRISMA guidel
    Document: To determine, in patients with coronavirus disease 2019 (COVID-19) infection, the associations of pulmonary embolism (PE) with mortality and risk factors for PE as well as the therapeutic benefit of anticoagulant prophylaxis. Embase, PubMed, Cochrane controlled trials register, and Web of Science databases were searched from inception to October 10, 2020. We included all published trials on PE in patients diagnosed with COVID-19 with eligibility of the trials assessed following the PRISMA guidelines. Sixteen clinical trials with 5826 patients were eligible. There were significant associations of PE with the male gender [odd ratio (OR) = 1.59, 95% CI 1.28–1.97], mechanical ventilation (OR = 3.71, 95% CI 2.57–5.36), intensive care unit admission (OR = 2.99, 95% CI 2.11–4.23), circulating D-dimer [mean difference (MD) = 5.04 µg/mL, 95% CI 3.67–6.42) and CRP (MD = 1.97 mg/dL, 95% CI 0.58– 3.35) concentrations without significant correlation between PE and mortality (OR = 1.31, 95% CI 0.82–2.08) as well as other parameters or comorbidities. After omitting one trial with strict patient selection criteria for anticoagulant prophylaxis, significant prophylactic benefit was noted (OR = 0.31, 95% CI 0.1–0.91). Our findings identified the risk factors associated with PE in COVID-19 patients and supported the therapeutic benefit of anticoagulant prophylaxis against PE in this patient population.

    Search related documents:
    Co phrase search for related documents
    • abstract title and address need: 1, 2
    • abstract title and admission status: 1
    • abstract title and low incidence: 1
    • abstract title and low quality: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15
    • abstract title and low quality study: 1
    • accurate interpretation and address need: 1, 2
    • acute myocardial infarction and admission status: 1
    • acute myocardial infarction and low incidence: 1
    • acute myocardial infarction and low quality: 1, 2, 3
    • acute respiratory distress syndrome and address need: 1, 2, 3, 4, 5, 6, 7, 8, 9
    • acute respiratory distress syndrome and admission status: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13
    • acute respiratory distress syndrome and low incidence: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13
    • acute respiratory distress syndrome and low quality: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13
    • acute respiratory distress syndrome obesity and address need: 1
    • address need and low quality: 1, 2, 3, 4, 5