Selected article for: "bayesian inference and epidemic outbreak"
Author: Nathan D. Grubaugh; Sharada Saraf; Karthik Gangavarapu; Alexander Watts; Amanda L. Tan; Rachel J. Oidtman; Jason T. Ladner; Glenn Oliveira; Nathaniel L. Matteson; Moritz U.G. Kraemer; Chantal B.F. Vogels; Aaron Hentoff; Deepit Bhatia; Danielle Stanek; Blake Scott; Vanessa Landis; Ian Stryker; Marshall R. Cone; Edgar W. Kopp; Andrew C. Cannons; Lea Heberlein-Larson; Stephen White; Leah D. Gillis; Michael J. Ricciardi; Jaclyn Kwal; Paola K. Lichtenberger; Diogo M. Magnani; David I. Watkins; Gustavo Palacios; Davidson H. Hamer; Lauren M. Gardner; T. Alex Perkins; Guy Baele; Kamran Khan; Andrea Morrison; Sharon Isern; Scott F. Michael; Kristian G. Andersen
Title: International travelers and genomics uncover a ‘hidden’ Zika outbreak
  • Document date: 2018_12_14
    • ID: lh6zul8l_16
    Snippet: We constructed phylogenetic trees using time-resolved Bayesian inference (Fig. 3A) and maximum likelihood reconstruction (Fig. S4) . We found that the Zika virus lineages in Cuba clustered with other virus genomes from the Americas, showing that the outbreak in Cuba was a continuation of the epidemic in the Americas, as opposed to introductions from ongoing Zika outbreaks in Asia Watts et al., 2018) (Fig. 3A) . Based on the placement of the Zika .....
    Document: We constructed phylogenetic trees using time-resolved Bayesian inference (Fig. 3A) and maximum likelihood reconstruction (Fig. S4) . We found that the Zika virus lineages in Cuba clustered with other virus genomes from the Americas, showing that the outbreak in Cuba was a continuation of the epidemic in the Americas, as opposed to introductions from ongoing Zika outbreaks in Asia Watts et al., 2018) (Fig. 3A) . Based on the placement of the Zika virus genomes from Cuba, we found evidence for one introduction from Central America (Fig. 3B , clade '1-Cuba') and at least two from the Caribbean (Fig. 3A, 3B , clades '2-Cuba', '3-Cuba', and '4-Cuba'); however the placement of clade '4-Cuba' is ambiguous, as it clusters with clade '3-Cuba' in the maximum likelihood tree (Fig. S4) , and may not be a seperate introduction (Fig. S4) .

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