Selected article for: "global health and limited resource"
Author: de Sá Magalhães, Salomé; Keshavarz-Moore, Eli
Title: Pichia pastoris (Komagataella phaffii) as a Cost-Effective Tool for Vaccine Production for Low- and Middle-Income Countries (LMICs)
  • Cord-id: ddozzmqv
  • Document date: 2021_8_31
    • ID: ddozzmqv
    Snippet: Vaccination is of paramount importance to global health. With the advent of the more recent pandemics, the urgency to expand the range has become even more evident. However, the potential limited availability and affordability of vaccines to resource low- and middle-income countries has created a need for solutions that will ensure cost-effective vaccine production methods for these countries. Pichia pastoris (P. pastoris) (also known as Komagataella phaffii) is one of the most promising candida
    Document: Vaccination is of paramount importance to global health. With the advent of the more recent pandemics, the urgency to expand the range has become even more evident. However, the potential limited availability and affordability of vaccines to resource low- and middle-income countries has created a need for solutions that will ensure cost-effective vaccine production methods for these countries. Pichia pastoris (P. pastoris) (also known as Komagataella phaffii) is one of the most promising candidates for expression of heterologous proteins in vaccines development. It combines the speed and ease of highly efficient prokaryotic platforms with some key capabilities of mammalian systems, potentially reducing manufacturing costs. This review will examine the latest developments in P. pastoris from cell engineering and design to industrial production systems with focus on vaccine development and with reference to specific key case studies.

    Search related documents:
    Co phrase search for related documents
    • acute respiratory syndrome and adcc antibody dependent cellular cytotoxicity: 1
    • acute respiratory syndrome and live comprise: 1
    • acute respiratory syndrome and lmic effective: 1
    • acute respiratory syndrome and long development time: 1, 2, 3
    • acute respiratory syndrome and long term immunity: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29
    • acute respiratory syndrome and low capital: 1
    • acute respiratory syndrome and low cell concentration: 1
    • acute respiratory syndrome and low cost produce: 1
    • acute respiratory syndrome and low cost production: 1, 2, 3, 4, 5, 6, 7, 8
    • acute respiratory syndrome and low efficiency: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17
    • acute respiratory syndrome and low number: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62
    • ad alzheimer disease and low number: 1