A special case of COVID-19 with long duration of viral shedding for 49 days

Li Tan; Xia Kang; Bo Zhang; Shangen Zheng; Bo Liu; Tiantian Yu; Fan Yang; Qiongshu Wang; Hongming Miao

Although evidences collected from these two cases indicate a better prognosis, patients with long duration of viral shedding in mild type are likely to be neglected in crowd and may persist infecting surroundings and cause a new outbreak. The viral tests of Case 1 once changed into negative on illness days 47. However, it reversed into positive on illness days 49 (Fig. 1A) . It is likely that the virus and the host got a dynamic balance. The viral load and the indicators of immune cells both maintained stable (Fig. 2) . Although the viral duplication was suppressed, immune cells cannot clear out the virus. The Case 1 may tend to be a chronic infected case without infusion treatment, the . CC-BY-NC-ND 4.0 International license It is made available under a is the author/funder, who has granted medRxiv a license to display the preprint in perpetuity.