Author: Erdoğan, Mehmet; Öztürk, Selçuk; Erdöl, Mehmet Akif; Kasapkara, Ahmet; Beşler, Muhammed Said; Kayaaslan, Bircan; Hasanoğlu, İmran; Durmaz, Tahir; Güner, Rahmet
Title: Prognostic utility of pulmonary artery and ascending aorta diameters derived from computed tomography in COVIDâ€19 patients Cord-id: z9opvznb Document date: 2021_8_6
ID: z9opvznb
Snippet: AIM: Chest computed tomography (CT) imaging plays a diagnostic and prognostic role in Coronavirus disease 2019 (COVIDâ€19) patients. This study aimed to investigate and compare predictive capacity of main pulmonary artery diameter (MPA), ascending aorta diameter (AAo), and MPAâ€toâ€AAo ratio to determine inâ€hospital mortality in COVIDâ€19 patients. MATERIALS AND METHODS: This retrospective study included 255 hospitalized severe or critical COVIDâ€19 patients. MPA was measured at the level
Document: AIM: Chest computed tomography (CT) imaging plays a diagnostic and prognostic role in Coronavirus disease 2019 (COVIDâ€19) patients. This study aimed to investigate and compare predictive capacity of main pulmonary artery diameter (MPA), ascending aorta diameter (AAo), and MPAâ€toâ€AAo ratio to determine inâ€hospital mortality in COVIDâ€19 patients. MATERIALS AND METHODS: This retrospective study included 255 hospitalized severe or critical COVIDâ€19 patients. MPA was measured at the level of pulmonary artery bifurcation perpendicular to the direction of the vessel through transverse axial images and AAo was measured by using the same CT slice at its maximal diameter. MPAâ€toâ€AAo ratio was calculated by division of MPA to AAo. RESULTS: Multivariate logistic regression model yielded MPA ≥29.15 mm (OR: 4.95, 95% CI: 2.01–12.2, p = 0.001), MPA (OR: 1.28, 95% CI: 1.13–1.46, p < 0.001), AAo (OR: .90, 95% CI: .81–.99, p = 0.040), and MPAâ€toâ€AAo ratio ≥.82 (OR: 4.67, 95% CI: 1.86–11.7, p = 0.001) as independent predictors of inâ€hospital mortality. Timeâ€dependent multivariate Coxâ€proportion regression model demonstrated MPA ≥29.15 mm (HR: 1.96, 95% CI: 1.03–3.90, p = 0.047) and MPA (HR: 1.08, 95% CI: 1.01–1.17, p = 0.048) as independent predictors of inâ€hospital mortality, whereas AAo and MPAâ€toâ€AAo ratio did not reach statistical significance. CONCLUSION: Pulmonary artery enlargement strongly predicts inâ€hospital mortality in hospitalized COVIDâ€19 patients. MPA, which can be calculated easily from chest CT imaging, can be beneficial in the prognostication of these patients.
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