Author: Kwang Su Kim; Keisuke Ejima; Yusuke Ito; Shoya Iwanami; Hirofumi Ohashi; Yoshiki Koizumi; Yusuke Asai; Shinji Nakaoka; Koichi Watashi; Robin N Thompson; Shingo Iwami
Title: Modelling SARS-CoV-2 Dynamics: Implications for Therapy Document date: 2020_3_27
ID: 09r4d3nu_18
Snippet: There are a number of potential transmission routes of SARS-CoV-2, 185 including direct person-to-person transmission due to viral particle inhalation and 186 contact transmission due to contact with nasal/oral/eye mucuous membranes. The virus production effectively reduces AUC of SARS-CoV-2 load; for example, if the 193 therapy can reduce more than 90% of de novo infections and is initiated 3 days after 194 symptoms onset, the viral load AUC is .....
Document: There are a number of potential transmission routes of SARS-CoV-2, 185 including direct person-to-person transmission due to viral particle inhalation and 186 contact transmission due to contact with nasal/oral/eye mucuous membranes. The virus production effectively reduces AUC of SARS-CoV-2 load; for example, if the 193 therapy can reduce more than 90% of de novo infections and is initiated 3 days after 194 symptoms onset, the viral load AUC is expected to be reduced by 81.4% (Fig. 3DE) . 195
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