Selected article for: "case infection and fatality rate"
Author: Ashish Goyal; E. Fabian Cardozo-Ojeda; Joshua T Schiffer
Title: Potency and timing of antiviral therapy as determinants of duration of SARS CoV-2 shedding and intensity of inflammatory response
  • Document date: 2020_4_14
    • ID: d7stppv5_2
    Snippet: It is imperative that optimal treatment strategies of COVID-19 are identified during the first wave of infection to ensure that the case fatality rate is lower during subsequent local epidemics. To date, selection of antiviral agents has been empirical and guided by limited or absent data. The window to conduct definitive clinical trials is likely to be narrow given that flatten the curve efforts are predicted to slow local epidemics, albeit temp.....
    Document: It is imperative that optimal treatment strategies of COVID-19 are identified during the first wave of infection to ensure that the case fatality rate is lower during subsequent local epidemics. To date, selection of antiviral agents has been empirical and guided by limited or absent data. The window to conduct definitive clinical trials is likely to be narrow given that flatten the curve efforts are predicted to slow local epidemics, albeit temporarily. Therefore, effective tools are urgently needed to optimize the design of these trials.

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