Author: Daniela Weiskopf; Katharina S. Schmitz; Matthijs P. Raadsen; Alba Grifoni; Nisreen M.A. Okba; Henrik Endeman; Johannes P.C. van den Akker; Richard Molenkamp; Marion P.G. Koopmans; Eric C.M. van Gorp; Bart L. Haagmans; Rik L. de Swart; Alessandro Sette; Rory Dylan de Vries
Title: Phenotype of SARS-CoV-2-specific T-cells in COVID-19 patients with acute respiratory distress syndrome Document date: 2020_4_18
ID: 97gme3pl_12
Snippet: More characteristic Th2 cytokines (IL-5, IL-13, IL-9 and IL-10) were also consistently detected, albeit at low levels. IL-6 levels were not different between COVID-19 patients and HC, while IL-4 and IL-21 could not be detected at all. Antigen-specific production of cytokines related to a Th17 response was mixed; IL-17 production was not different between patients and HC, whereas IL-22 could be detected. Thus, stimulation of PBMC from COVID-19 pat.....
Document: More characteristic Th2 cytokines (IL-5, IL-13, IL-9 and IL-10) were also consistently detected, albeit at low levels. IL-6 levels were not different between COVID-19 patients and HC, while IL-4 and IL-21 could not be detected at all. Antigen-specific production of cytokines related to a Th17 response was mixed; IL-17 production was not different between patients and HC, whereas IL-22 could be detected. Thus, stimulation of PBMC from COVID-19 patients with MP led to a balanced production of IFNg, TNFa, IL-2, IL-5, IL-13, IL-9, IL-10 and IL-22. the author/funder, who has granted medRxiv a license to display the preprint in perpetuity.
Search related documents:
Co phrase search for related documents- consistently detect and low level: 1
Co phrase search for related documents, hyperlinks ordered by date