Author: Yafei Wang; Randy Heiland; Morgan Craig; Courtney L. Davis; Ashlee N Ford Versypt; Adrianne Jenner; Jonathan Ozik; Nicholson Collier; Chase Cockrell; Andrew Becker; Gary An; James A. Glazier; Aarthi Narayanan; Amber M Smith; Paul Macklin
Title: Rapid community-driven development of a SARS-CoV-2 tissue simulator Document date: 2020_4_5
ID: lq4tcyh4_14
Snippet: 1) Virus dissemination in epithelial tissue 2) Virus binding, endocytosis, replication, and exocytosis 3) Infected cell responses, including changes to metabolism, secreted signals, and death 4) Inflammatory response 5) Ramp up the immune response (particularly in lymph nodes) 6) Immune cell infiltration 7) Immune cell predation of infected and other cells. 8) Tissue damage by death of infected cells and immune cells 9) Early fluid leakage that c.....
Document: 1) Virus dissemination in epithelial tissue 2) Virus binding, endocytosis, replication, and exocytosis 3) Infected cell responses, including changes to metabolism, secreted signals, and death 4) Inflammatory response 5) Ramp up the immune response (particularly in lymph nodes) 6) Immune cell infiltration 7) Immune cell predation of infected and other cells. 8) Tissue damage by death of infected cells and immune cells 9) Early fluid leakage that can be regarded as an early marker or surrogate for ARDS
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