Author: Monique R. Ambrose; Adam J. Kucharski; Pierre Formenty; Jean-Jacques Muyembe-Tamfum; Anne W. Rimoin; James O. Lloyd-Smith
Title: Quantifying transmission of emerging zoonoses: Using mathematical models to maximize the value of surveillance data Document date: 2019_6_19
ID: f14u2sz5_32
Snippet: The district-level model estimates a reproductive number for human monkeypox of 0.38 554 (0.31-0.45 95% CI). This value is slightly higher than previous estimates of R for the 1980s DRC 555 monkeypox dataset, which was estimated as 0. The copyright holder for this preprint (which was not peer-reviewed) is the author/funder. It . https://doi.org/10.1101/677021 doi: bioRxiv preprint of human-to-human transmission than the district-level model due t.....
Document: The district-level model estimates a reproductive number for human monkeypox of 0.38 554 (0.31-0.45 95% CI). This value is slightly higher than previous estimates of R for the 1980s DRC 555 monkeypox dataset, which was estimated as 0. The copyright holder for this preprint (which was not peer-reviewed) is the author/funder. It . https://doi.org/10.1101/677021 doi: bioRxiv preprint of human-to-human transmission than the district-level model due to their larger broader contact 564 zone sizes. The size of the DRC's districts and administrative subregions used for the district-565 level model vary in size, but average around fifteen thousand square kilometers, or around one 566 hundred forty kilometers across, encompassing a much greater distance than most human-to-567 human transmission events likely occur over. We therefore expect that the true value of R is 568 bounded by the estimates of the locality-level and the district-level models. 569
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