Selected article for: "cell binding and host cell binding"

Author: Ke Wang; Wei Chen; Yu-Sen Zhou; Jian-Qi Lian; Zheng Zhang; Peng Du; Li Gong; Yang Zhang; Hong-Yong Cui; Jie-Jie Geng; Bin Wang; Xiu-Xuan Sun; Chun-Fu Wang; Xu Yang; Peng Lin; Yong-Qiang Deng; Ding Wei; Xiang-Min Yang; Yu-Meng Zhu; Kui Zhang; Zhao-Hui Zheng; Jin-Lin Miao; Ting Guo; Ying Shi; Jun Zhang; Ling Fu; Qing-Yi Wang; Huijie Bian; Ping Zhu; Zhi-Nan Chen
Title: SARS-CoV-2 invades host cells via a novel route: CD147-spike protein
  • Document date: 2020_3_14
  • ID: 5hpbjkft_3
    Snippet: The interaction of SP and ACE2 contributes to the SARS-CoV invasion for host cells [6] . Interestingly, the structure of SARS-CoV-2 SP is highly similar to that of SARS-CoV SP, and SARS-CoV-2 SP binds to ACE2 with a higher affinity than SARS-CoV SP, indicative of a stronger ability of SAR-CoV-2 to invade host cells [7, 8] . In addition to ACE2, other receptors for SP binding on the host cell membrane remain unclear......
    Document: The interaction of SP and ACE2 contributes to the SARS-CoV invasion for host cells [6] . Interestingly, the structure of SARS-CoV-2 SP is highly similar to that of SARS-CoV SP, and SARS-CoV-2 SP binds to ACE2 with a higher affinity than SARS-CoV SP, indicative of a stronger ability of SAR-CoV-2 to invade host cells [7, 8] . In addition to ACE2, other receptors for SP binding on the host cell membrane remain unclear.

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