Author: Kumari G. Lokugamage; Adam Hage; Craig Schindewolf; Ricardo Rajsbaum; Vineet D. Menachery
Title: SARS-CoV-2 is sensitive to type I interferon pretreatment Document date: 2020_3_9
ID: 2w0zr9c0_16
Snippet: we find that both SARS-CoV and SARS-CoV-2 replicate with similar kinetics, peaking 48 hours 80 post infection (Fig. 1A) . While SARS-CoV-2 titer had slightly lower viral titers at 24 hours post 81 infection, the results were statistically different between the novel CoV and the original epidemic 82 strain. By 48 hours, replication of both viruses had plateaued and significant cytopathic effect 83 (CPE) was observed for both SARS-CoV and SARS-CoV-.....
Document: we find that both SARS-CoV and SARS-CoV-2 replicate with similar kinetics, peaking 48 hours 80 post infection (Fig. 1A) . While SARS-CoV-2 titer had slightly lower viral titers at 24 hours post 81 infection, the results were statistically different between the novel CoV and the original epidemic 82 strain. By 48 hours, replication of both viruses had plateaued and significant cytopathic effect 83 (CPE) was observed for both SARS-CoV and SARS-CoV-2 infections. Together, the results 84 indicated that SARS-CoV and SARS-CoV-2 replicate with similar replication kinetics in Vero E6 85
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