Author: Uzun, Tuğçenur; Toptas, Orcun
Title: Artesunate: could be an alternative drug to chloroquine in COVID-19 treatment? Cord-id: rc5bn6jc Document date: 2020_5_28
ID: rc5bn6jc
Snippet: SARS (Severe Acute Respiratory Syndrome Coronavirus)-CV-2 (2019-nCov), which showed up in China in December 2019 and spread all over the world, has becomed a serious health problem. An effective, safe and proven treatment has not yet been found. Chloroquine has been recommended by some authors to be used for the treatment of patients infected with this virus however chloroquine may have side effects and drug resistance problems. Artesunate is a semisynthetic derivative of artemisinin, an antimal
Document: SARS (Severe Acute Respiratory Syndrome Coronavirus)-CV-2 (2019-nCov), which showed up in China in December 2019 and spread all over the world, has becomed a serious health problem. An effective, safe and proven treatment has not yet been found. Chloroquine has been recommended by some authors to be used for the treatment of patients infected with this virus however chloroquine may have side effects and drug resistance problems. Artesunate is a semisynthetic derivative of artemisinin, an antimalarial drug. Artesunate was thought to be an effective treatment for covid-19 because of its anti-inflammatory activity, NF-κB (nuclear Factor kappa B)-coronavirus effect and chloroquine-like endocytosis inhibition mechanism.
Search related documents:
Co phrase search for related documents- activity increase and adaptive immune response: 1
- activity increase and lung disease: 1, 2
- activity increase and lung injury: 1, 2, 3, 4, 5, 6, 7, 8
- acute lung injury and adaptive immune response: 1, 2, 3, 4, 5
- acute lung injury and lung disease: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25
- acute lung injury and lung disease pathogenesis: 1, 2, 3, 4, 5, 6, 7
- acute lung injury and lung injury: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25
- acute lung injury and lupus erythematosus: 1, 2
- acute lung injury fatal inflammatory response and lung injury: 1
- adaptive immune response and lung disease: 1, 2, 3, 4, 5, 6
- adaptive immune response and lung injury: 1, 2, 3, 4, 5, 6, 7, 8, 9
- adaptive immune response and lupus erythematosus: 1
- lung disease and lupus erythematosus: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18
- lung injury and lupus erythematosus: 1, 2
Co phrase search for related documents, hyperlinks ordered by date