Author: Helen Y. Chu; Michael Boeckh; Janet A. Englund; Michael Famulare; Barry R. Lutz; Deborah A Nickerson; Mark J. Rieder; Lea M Starita; Amanda Adler; Elisabeth Brandstetter; Chris D. Frazar; Peter D. Han; Reena K. Gularti; James Hadfield; Michael L. Jackson; Anahita Kiavand; Louise E. Kimball; Kirsten Lacombe; Jennifer Logue; Victoria Lyon; Kira L. Newman; Thomas R. Sibley; Monica L. Zigman Suschsland; Caitlin Wolf; Jay Shendure; Trevor Bedford
Title: The Seattle Flu Study: a multi-arm community-based prospective study protocol for assessing influenza prevalence, transmission, and genomic epidemiology Document date: 2020_3_6
ID: 4nmc356g_10
Snippet: Community-wide studies provide a mechanism to identify influenza among individuals who do not present for care and who may provide the first signal of an impending pandemic (12) . Previous community-wide studies of influenza, including family-based prospective studies, conducted in the 20 th century, have provided important data on transmission dynamics, including the role of households and schools in driving seasonal epidemics. More recent prosp.....
Document: Community-wide studies provide a mechanism to identify influenza among individuals who do not present for care and who may provide the first signal of an impending pandemic (12) . Previous community-wide studies of influenza, including family-based prospective studies, conducted in the 20 th century, have provided important data on transmission dynamics, including the role of households and schools in driving seasonal epidemics. More recent prospective studies employing molecular detection methods have highlighted the role of asymptomatic individuals in disease transmission (13) . However, a common limitation of community-based studies is they do not routinely integrate their data with inpatient hospital and ambulatory care surveillance to understand the transmission and burden of influenza at a population level within a specific geographic area.
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