The cross-sectional study of hospitalized coronavirus disease 2019 patients in Xiangyang, Hubei province

Jinwei Ai; Junwen Chen; Yong Wang; Xiaoyun Liu; Wufeng Fan; Gaojing Qu; Meiling Zhang; Shengduo Polo Pei; Bowen Tang; Shuai Yuan; Yang Li; Lisha Wang; Guoxin Huang; Bin Pei

Thus, the rate of missed diagnosis is relatively high if only use single real-time RT-PCR test [24] . The rate of right diagnosis is 88% for CT examination at the first time and all firsttime diagnosed patients had fever and cough. RNA detection combined with CT at the first diagnosis, along with clinical manifestations can greatly increase the sensitivity and reduce the rate of missed diagnosis. The cumulative positive rate of three times of throat swabs virus RNA tests was 96%, and the cumulative diagnostic coincidence rate of two times CT tests and nucleic acid tests reached 98%. The simultaneous application of two methods can basically detect all potential patients. Based on this, we inferred that "3+2 " combined strategy can diagnose most SARS-CoV-2 infected patients, which had great reference value for the diagnosis of "clinically diagnosed cases". The application of the "3+2" diagnostic method was conducive to the effective control of the source of infection and was a key point to improve SARS-CoV-2 prevention and control.