Author: Ferrucci, S.; Romagnuolo, M.; Angileri, L.; Berti, E.; Tavecchio, S.
Title: Safety of dupilumab in severe atopic dermatitis and infection of Covidâ€19: two case reports Cord-id: 6n9043d4 Document date: 2020_4_24
ID: 6n9043d4
Snippet: Dupilumab is a fully human monoclonal antibody against the alfa subunit of interleukin (IL)â€4 receptor that blocks signalling from both ILâ€4 and ILâ€13, which are key type 2 cytokines in the pathophysiology of atopic dermatitis (AD). It shows good efficacy with a rapid response and good safety with few side effects. In a paper of Deleuran et al. the authors showed long term safety and efficacy of dupilumab; they reported viral upper respiratory tract infection, cough and influenza in about
Document: Dupilumab is a fully human monoclonal antibody against the alfa subunit of interleukin (IL)â€4 receptor that blocks signalling from both ILâ€4 and ILâ€13, which are key type 2 cytokines in the pathophysiology of atopic dermatitis (AD). It shows good efficacy with a rapid response and good safety with few side effects. In a paper of Deleuran et al. the authors showed long term safety and efficacy of dupilumab; they reported viral upper respiratory tract infection, cough and influenza in about 2% of patients.
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