Author: Ivan Mercurio; Vincenzo Tragni; Francesco Busco; Anna De Grassi; Ciro Leonardo Pierri
Title: Protein structure analysis of the interactions between SARS-CoV-2 spike protein and the human ACE2 receptor: from conformational changes to novel neutralizing antibodies Document date: 2020_4_18
ID: mswmkgl4_59
Snippet: Starting from that observation we have also proposed a set of modifications of m396 CDR residues resulting in a higher specific antibody, to be expressed and tested on cultured cells. Along the development of our antibody engineering modeling session an important paper was published and another is under revision in support of the hypothesis that m396 may be able to bind SARS-CoV-2 spike protein (61, 62) ......
Document: Starting from that observation we have also proposed a set of modifications of m396 CDR residues resulting in a higher specific antibody, to be expressed and tested on cultured cells. Along the development of our antibody engineering modeling session an important paper was published and another is under revision in support of the hypothesis that m396 may be able to bind SARS-CoV-2 spike protein (61, 62) .
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