Author: Minfeng Liao; Yang Liu; Jin Yuan; Yanling Wen; Gang Xu; Juanjuan Zhao; Lin Chen; Jinxiu Li; Xin Wang; Fuxiang Wang; Lei Liu; Shuye Zhang; Zheng Zhang
Title: The landscape of lung bronchoalveolar immune cells in COVID-19 revealed by single-cell RNA sequencing Document date: 2020_2_26
ID: 8l1vfsbc_22
Snippet: robust and early T cell response played crucial roles in viral clearance during acute respiratory infections [14] . After exclusion of contaminated clusters, our clustering analysis of T and NK lymphocytes identified 5 major subsets ( Figure 3A ) based on the typical T and NK cell markers ( Figure 3B ). NK cells highly expressed KLRF1, KLRC1 and KLRD1. CD8 + T cells expressed CD8A and CD8B. The CCR7 + cells expressing CD4 and IL7R were likely CD4.....
Document: robust and early T cell response played crucial roles in viral clearance during acute respiratory infections [14] . After exclusion of contaminated clusters, our clustering analysis of T and NK lymphocytes identified 5 major subsets ( Figure 3A ) based on the typical T and NK cell markers ( Figure 3B ). NK cells highly expressed KLRF1, KLRC1 and KLRD1. CD8 + T cells expressed CD8A and CD8B. The CCR7 + cells expressing CD4 and IL7R were likely CD4 + T cells, Treg cells were CTLA4 + FOXP3 + IL2RA + , and proliferating cells were TYMS + MKI67 + .
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