Author: Xianding Deng; Wei Gu; Scot Federman; Louis Du Plessis; Oliver Pybus; Nuno Faria; Candace Wang; Guixia Yu; Chao-Yang Pan; Hugo Guevara; Alicia Sotomayor-Gonzalez; Kelsey Zorn; Allan Gopez; Venice Servellita; Elaine Hsu; Steve Miller; Trevor Bedford; Alexander Greninger; Pavitra Roychoudhury; Michael Famulare; Helen Y Chu; Jay Shendure; Lea Starita; Catie Anderson; Karthik Gangavarapu; Mark Zeller; Emily Spencer; Kristian Andersen; Duncan MacCannell; Suxiang Tong; Gregory Armstrong; Clinton Paden; Yan Li; Ying Zhang; Scott Morrow; Matthew Willis; Bela Matyas; Sundari Mase; Olivia Kasirye; Maggie Park; Curtis Chan; Alexander Yu; Shua Chai; Elsa Villarino; Brandon Bonin; Debra Wadford; Charles Y Chiu
Title: A Genomic Survey of SARS-CoV-2 Reveals Multiple Introductions into Northern California without a Predominant Lineage Document date: 2020_3_30
ID: cbc98t7x_20
Snippet: Public health containment measures such as prompt isolation and contact tracing, as performed in the Solano County and Santa Clara County clusters, become more difficult to maintain once a lineage becomes established in the community. Our data suggest concerning trends in this direction, such as the association between the WA1 lineage and communityacquired COVID-19 cases in several counties of Northern California, travel-associated introduction o.....
Document: Public health containment measures such as prompt isolation and contact tracing, as performed in the Solano County and Santa Clara County clusters, become more difficult to maintain once a lineage becomes established in the community. Our data suggest concerning trends in this direction, such as the association between the WA1 lineage and communityacquired COVID-19 cases in several counties of Northern California, travel-associated introduction of SARS-CoV-2 into the San Francisco Bay Area from New York state, and a virus from the lineage associated with a Santa Clara County cluster detected in a resident of Solano County. Social distancing interventions, such as the "shelter-in-place" directive that was issued by the governor of California on March 20, 2020, may assist in stemming community spread of imported cases. If interstate dissemination of SARS-CoV-2 lineages within the US is common, then the suspension of non-essential domestic and international long-range travel may be necessary to prevent further importation of new cases in California and other states.
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