Author: Alpana Waghmare; Elizabeth M Krantz; Subhasish Baral; Emma Vasquez; Tillie Loeffelholz; E. Lisa Chung; Urvashi Pandey; Jane Kuypers; Elizabeth R Duke; Keith R Jerome; Alexander L Greninger; Daniel B Reeves; Florian Hladik; E Fabian Cardozo-Ojeda; Michael Boeckh; Joshua T Schiffer
Title: Reliability of self-sampling for accurate assessment of respiratory virus viral and immunologic kinetics Document date: 2020_4_6
ID: 89s17ytr_20
Snippet: show that viral load may be predictive of COVID-19 severity 10 , it is equally plausible that the 280 intensity and phenotype of the early local cellular immune response plays a causal role in 281 limiting the extent of infection 28 . By following the molecular immune response closely with daily 282 sampling intervals, we also provide adequate data for mathematical models that can link 283 specific arms of the cellular immune response to pathogen.....
Document: show that viral load may be predictive of COVID-19 severity 10 , it is equally plausible that the 280 intensity and phenotype of the early local cellular immune response plays a causal role in 281 limiting the extent of infection 28 . By following the molecular immune response closely with daily 282 sampling intervals, we also provide adequate data for mathematical models that can link 283 specific arms of the cellular immune response to pathogen control in real time 22 , a goal that has 284 been difficult to attain for a majority of viral infections in humans. 285
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