Author: Dong, Peng; Ju, Xiangwu; Yan, Yiwu; Zhang, Siya; Cai, Menghua; Wang, Huaishan; Chen, Hui; Hu, Yu; Cui, Lianxian; Zhang, Jianmin; He, Wei
Title: ?d T Cells Provide Protective Function in Highly Pathogenic Avian H5N1 Influenza A Virus Infection Document date: 2018_12_4
ID: 0frb01wq_5
Snippet: In this study, we investigated the roles of γδ T cells in the defense against HPAI H5N1 viral infection. We found that γδ T cells provided crucial protective function during HPAI H5N1 viral infection. HPAI H5N1 viruses could directly activate γδ T cells via natural HA trimers, initiating γδ T cell-mediated innate and adoptive immune response. Our findings provide a further understanding the mechanism underlying γδ T cell-mediated innate.....
Document: In this study, we investigated the roles of γδ T cells in the defense against HPAI H5N1 viral infection. We found that γδ T cells provided crucial protective function during HPAI H5N1 viral infection. HPAI H5N1 viruses could directly activate γδ T cells via natural HA trimers, initiating γδ T cell-mediated innate and adoptive immune response. Our findings provide a further understanding the mechanism underlying γδ T cell-mediated innate and adoptive immune responses against HPAI H5N1 viral infection.
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